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Also, during treatment you should avoid grapefruit juice. Possible Side Effects The most common side effects with Tadalafil are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. Ask your personal physician for further information. Alert your personal physician as soon as possible. Taking tadalafil with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.










